Antipsychotics, also known as neuroleptics, are a class of drugs used to treat psychiatric disorders, such as schizophrenia, bipolar disorder, and psychotic depression. Antipsychotics work by changing the way certain neurotransmitters (mainly dopamine) act in the brain. This pharmacology lecture covers topics such as schizophrenia, role of dopamine in the development of psychosis, dopamine pathways in the brain (Mesolimbic, Mesocortical, Nigrostriatal, Tuberoinfundibular), positive & negative symptoms of schizophrenia, dopamine & serotonin receptors, mechanism of action and side effects of antipsychotic drugs (1st generation typical & 2nd generation atypical). Drugs mentioned include; Haloperidol, Fluphenazine, Prochlorperazine, Trifluoperazine, Chlorpromazine, Aripiprazole, Clozapine, Lurasidone, Olanzapine, Quetiapine, Risperidone, and Ziprasidone.
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Thank you so much for making me understand clearly… big thz
Good job done mate👊
Just like Anabol8cs,too sloppy .
please grant me copyright to put it on Chinese network!
Try Cannabis.(Or psilocybin).
Any way to contact you? Would need the pictures for a presentation
This was a very helpful video. Detailed however engaging. I have learned a lot in under 10 minutes 👏🏾 now I will study this so it sticks
Amazing video, this helped me understand the information so much more. Thank you!!
Hi everybodyyy! Hi DR NICK!
Thanks for making it simple, I really understand it now. 👌🏽
Modern day butchers.
Bipolar disorder is not a real diagnosis. Bipolar could be a word borrowed from industrial packaging, where nitrogen is used to extend the shelf life of the product. Otherwise it's an esoteric word used in psychiatry. (They don't take their own medication, and they have never worked in telecommunications).
Wow great…love you
Easy to understand review with simple visuals, my 1st video of yours, found it to be well done
Thank you. God bless/alhumdulillah
In atypical drug what is the role of serotonin??
How long does the side effects like weight gain last in the body?
is it effective to treat schizophrenia with antipsychotic combination rather than one.
I took depakote for schizophrenia it made me real sick and caused neuro inflammation and damage parts of my brain and they won't but the bad affects like neuro inflammation and music sounding bad and gaba receptor damage on google because they want to keep selling the drug for money and keep hurting or killing more people
I started risperidone about a month ago and I am finding g relief in symptoms. I was diagnosed with Pure O OCD and Marijuana induced Psychosis. I went from intrusive thoughts with insight to poor insight and then stuck in "analysis paralysis" for a couple of years. I really dont know how I made it this far to be honest. Everything went south roughly 4 years ago when I stopped taking my anti depressant medication Effexor. I was smoking pot heavily and decided that I wanted to do everything naturally and thought that marijuana would work as my drug of choice. This is also when serious delusions started happening. My gut is telling me that the effexor was working and the pot was causing me the paranoia and delusions. I really thought I was on the right track and "waking up " because I started looking st everything that's harmful and things that arent and quit smoking drinking and after a hospitalization quit smoking pot. I've been battling with severe anxiety and constantly stuck in my head ever since and like I said just the past 4 weeks I have found slight relief but still slip into analysis paralysis. Does anyone have any recommendation on whether or not I should go back to being on effexor where I believe I will be on this life long (tryed many natural remedies and lifestyle changes including minfulness) or should I stay on the Risperidone where I am finding relief? Any help would be greatly appreciated , thanks.
it will help chop off your arm you have to leave them on piss em out they are expensive
I love you man, you took pharma out of nightmare's list. big thanks
thank u so much 🌸💪
Can you put a french traduction plz!🌸
"Anti-psychotics" (neuroleptics) do not exert their therapeutic (pharmacological target) effects on psychosis (positive symptoms of schizophrenia) by rectifying a brain abnormality, such as a chemical imbalance, nor do they target any physiological process that produces the positive symptoms of schizophrenia, but rather neuroleptics suppress symptoms of schizophrenia, by a profound slowing up and dampening down of mental processes by putting a brake on dopaminergic neurotransmission – they arrest natural brain function. Neuroleptics are major tranquilizers, neurological inhibitors, suppressants and depressants of the central nervous system. Neuroleptic means "nerve seizing". Neuroleptics work to treat psychosis by disrupting normal brain function in the reward (mesolimbic) pathway, and in the mesocortical pathway – connecting to the frontal lobe (the part of our brain that makes us human). Neuroleptics do not exert their psychosis-treating effects by targeting an underlying brain abnormality, such as a chemical imbalance, i.e. dysregulation of the dopaminergic neurotransmitter system, ie. overactivity of dopamine neurotransmission in the dopaminergic pathways: mesolimbic (reward), mesocortical (humanity), nigrostriatal (target of antiparkinsonian agents), and tuberoinfundibular (hormones, i.e. prolactin). Neuroleptics do not reverse any known disease process. There is no (sufficient) evidence that a lesion in the dopaminergic pathways is the primary cause of schizophrenia. Neuroleptics seize the central nervous system, dampen down dopaminergic brain activity, suppress function by occupying 70% – 90% dopamine D2 receptors. Neuroleptics are first and foremost psychoactive drugs. Their psychoactive effects (their global alterations of physical and mental states) treat symptoms of schizophrenia. Neuroleptics are not antidotes for psychosis. Neuroleptics are not disease-specific treatments in schizophrenia, but rather mind altering agents producing such mental and physical alterations that suppress symptoms (superimpose upon the symptoms that they are treating). Neuroleptic effects (target and side effects) may be useful in treating (dampening down) psychotic states, but that depends on the context. They do not exert their therapeutic effects by reversing or rectifying a disease process, nor are they curative agents; they cannot cure psychosis, nor prevent, nor decrease the probability that one will become ill or lessen the severity of the illness (quite the contrary!).
Informative and scrupulous
Quietiapine, serokill, seroquHELL, this poisonous piece of garbage is worst than heroin, the side effects are much much worst than those of the heroin, Td, sexual dysfunction, high blood pressure, tiredness, blurred vision, alzheimer, falls, you BECAME UNABLE TO WORK, THIS IS A NEURO TOXIN! PURE POISON! AND IS EXTREMELY ADDICTIVE, IF YOU TRY TO GET OFF YOU CAN DIE! IS WORST THAN HEROIN! Be carefull!